The Czech Republic pulled off the first big shock of the tournament and what could be one of the biggest this summer after they downed Holland.
Outsiders for the clash against Frank de Boer’s side after they slumped to a third-place finish in Group D, many had Oranje through to the next round before a ball had been kicked.
But Matthijs De Ligt’s red card for a deliberate handball left the Dutch in the lurch as the Czech’s grew into the knockout clash.
Tomas Holes ensured that they capitalised on their extra man advantage with his thumping header before Patrik Schick edged closer to beating Milan Baros’ record at a European Championships.
A defeat in the final match against England and Croatia’s 3-1 win over Scotland meant that the Czechs slipped two places down the group standings only qualifying for the knockout phase after finishing as one of the best third-placed teams.
Left-back Jan Boril returns from suspension for the match but it will a tough call to make for Jaroslav Šilhavý after his replacement Pavel Kaderabek put in a solid performance to halt the threat of the Dutch.
Southgate happy England are playing away from Wembley for first time
With the support of millions around the world and the desire to play for Christian Eriksen, Denmark continue to march on.
They made easy work of Wales with their emphatic 4-0 win over Rob Page’s side in Amsterdam.
Kasper Dolberg’s brace helped tame the Dragons with his second coming at the expense of a poor clearance from Liverpool’s Neco Williams.
Joakim Maehle added to his tally for the tournament before Martin Braithwaite added the gloss to the win.
Meanwhile, Eriksen continues his recovery from the cardiac arrest he suffered during their opening match against Finland. He has since had an ICD implant and discharged from hospital.
Kasper Hjulmand made a number of changes for the win against Wales including Kasper Dolberg replacing Yusuf Poulsen. Mikkel Damsgaard should continue as a starter deputising for Eriksen after his impressive last two displays.
However, the Danes may be forced to sweat over the availability of captain Simon Kjaer after he limped off with a thigh injury during last weekends win.
The winner of this clash will play either England or Ukraine who play on Saturday with Gareth Southgate’s side heading into that match in Rome as favourites after their historic win over Germany.
The match has a trip to Wembley in the semi-final at stake for the victors.
How to watch Czech Republic vs Denmark
The quarter-final will be shown on ITV with coverage starting at 4pm ahead of the 5pm kick-off.
It will also be available to live stream on the ITV Hub.
Who is in charge?
Dutch referee Bjorn Kuipers will be the man in the middle for the clash.
It will be his third match of the tournament and his second in charge of Denmark after he was in charge of their 2-1 defeat to Belgium on matchday two.